3 published reviews from patients treated at Optimal Bio in Cary, United States, averaging 3.7 out of 5. Every review is moderated before it appears.
Back to the full Optimal Bio profile3 reviews
Individual results vary and are not typical or guaranteed. Case studies and testimonials reflect one person's experience.
Third-party sources, summarised by our editors and quoted where a reviewer said it best. These are not Optimal Bio's reviews on this site and are not counted in its rating here.
4.9out of 5 on Google from 742 ratings
The Cary listing carries a 4.9 rating across 742 Google reviews. Google's own topic tally shows reviewers mostly discussing bioidentical hormone replacement therapy, pellet placement and testosterone therapy, with frequent mention of lab work and results review, plus thyroid and menopausal symptoms. Doctor knowledge is the most cited staff theme.
Most-mentioned on Google
Checked . Figures on the source may have changed since. View the Google listing
Reddit discussion is very thin. One 2022 question, crossposted to r/NorthCarolina and r/raleigh, drew a single substantive reply: a self described patient said pellet therapy eased her menopause symptoms and rated the initial lab workup worthwhile. The original poster found the phone consultation noticeably sales driven.
Recurring points
Threads read
Titles below are the Reddit posters' own wording, not ours.
Checked . Figures on the source may have changed since.
The reviews are about hormone pellet therapy. Two long-term patients, one on testosterone and thyroid treatment for over ten years and one receiving pellets quarterly, report more energy and improvements in anxiety, low mood and focus, and the second names Rachel for checking levels and adjusting between visits. A third, a pellet patient since May 2024, says the clinic declined a scheduled testosterone pellet in January 2026 after they began hormone therapy through another provider.
All 3 reviews published for Optimal Bio on this site.
Experience
I receive pellets quarterly - it has been a life changing experience. The constant anxiety, feeling tired and depressed, inability to focus...gone! It's also nice not to mess with patches or creams. I see Rachel - she's awesome! She checks my levels, answers any questions and makes adjustments as needed. I've been on these pellets for many years and I highly recommend Optimal Bio.
Experience
Buyer beware. I was a moderately* content T pellet patient with Optimal Bio from May 2024 through early 2026. However, when I decided to start HRT (estradiol gel and progesterone capsules) through another provider in October 2025, Optimal Bio refused to provide my scheduled T pellet in January 2026. The decision felt abrupt and unexpected, and the explanations they offered didn't make scientific sense given my medical background. My impression is that they were simply unhappy I chose not to buy into their pellet-based E therapy.
Experience
Optimal Bio has been taking care of my testosterone and thyroid needs for well over 10yrs. They took me from constantly feeling tired and worn out, to having the energy to be active, get things done, and enjoy life. I'm 69yrs old. It keeps me stepping, but I can keep pace with my grandson, and I know he loved it.
Every review here comes from someone who says they were treated at Optimal Bio in Cary, North Carolina. Our moderation team reads each one before it goes up. We check that it describes a real visit and stays inside our content rules. We do not check whether the treatment worked. Optimal Bio gets no say either way: the clinic cannot approve a review, edit one, or have one taken down. None of the reviews here are treatment-verified yet, so read them as first-hand accounts rather than confirmed records.
Optimal Bio is a regenerative-medicine provider based in Cary, North Carolina, operating since 2012. Patients most often come to it for Anti-Aging / Longevity and Erectile / Sexual Health. Its listed accreditations are Board-Certified Physicians.
Keep that spread in mind while you read. A review of a anti-aging / longevity case tells you little about how the clinic handles the rest of what it offers, and a patient who lives nearby has a very different week from one who flew in for a single visit.
Reviews are one input. Ask Optimal Bio for the rest directly: which cell source and preparation they would use for your condition, who performs the procedure, what the quoted price covers, what follow-up you get, and what evidence they are relying on. Vague answers to any of those are worth noticing.
The full Optimal Bio profile has the team, accreditations and treatment list. There is a separate page on what Optimal Bio costs, and you can read how we rank and verify clinics and how we moderate reviews. For anything clinical, ask a doctor who knows your history.